Acetyl Tetrapeptide-5

TL;DR. This ingredient is a skin-conditioning peptide used primarily in eye and facial products to support a smoother look and reduce the appearance of puffiness. It is typically used as a low-level active rather than as a structural emulsifier, solvent, or preservative.

What does Acetyl Tetrapeptide-5 do in a cosmetic formula?

This ingredient is a skin-conditioning peptide used primarily in eye and facial products to support a smoother look and reduce the appearance of puffiness. It is typically used as a low-level active rather than as a structural emulsifier, solvent, or preservative.

Is Acetyl Tetrapeptide-5 clean?

From a clean-beauty perspective, it is generally well tolerated and is not a common fragrance allergen or restricted-list ingredient. The main caveat is that visible-benefit claims often rely on supplier data, so DARE treats it as acceptable but not strongly evidence-leading.

Is Acetyl Tetrapeptide-5 sustainable?

This material is usually lab synthesized from amino-acid building blocks, so it does not carry major palm, mica, or petrochemical-film persistence issues. Its small peptide structure is expected to be biodegradable, although production can involve specialty solvents, coupling agents, and purification steps.

Is Acetyl Tetrapeptide-5 COSMOS-approved?

It is generally not a strong fit for COSMOS-organic or COSMOS-natural formulas unless a supplier can document compliant origin and processing for the finished material. Its Green Chemistry profile is mixed, with low use levels and biodegradability on the positive side, but synthetic processing and solvent-intensive manufacture as caveats.

How does Acetyl Tetrapeptide-5 work chemically?

The molecule is a short, N-capped chain of four amino-acid residues, designed for water-phase delivery in serums, gels, and eye products. Typical cosmetic use is low, often in the active range below 1 percent as supplied, and it is best formulated in moderate pH systems and protected from harsh heat or strong oxidizing conditions.

Last updated 2026-05-13