Ceramide 6-II ●
TL;DR. This ingredient is a skin-conditioning barrier lipid used to support the stratum corneum’s lamellar structure and reduce water loss. It is typically included in moisturizers, barrier creams, and scalp or body products rather than as a standalone active.
What does Ceramide 6-II do in a cosmetic formula?
This ingredient is a skin-conditioning barrier lipid used to support the stratum corneum’s lamellar structure and reduce water loss. It is typically included in moisturizers, barrier creams, and scalp or body products rather than as a standalone active.
Is Ceramide 6-II clean?
From a clean-beauty perspective, it is generally well-tolerated and not a common allergen or restricted-list concern. The main review point is how it is made, since some versions are biofermented or plant-derived while others rely on more conventional synthetic processing.
Is Ceramide 6-II sustainable?
This material is usually produced through biotechnology, plant-derived lipid chemistry, or synthesis, with animal-derived sourcing now uncommon in modern cosmetic supply chains. It is a biodegradable lipid used at low levels, though feedstock traceability and solvent choices can vary by supplier.
Is Ceramide 6-II COSMOS-approved?
It may be permitted under COSMOS-natural when the feedstocks and manufacturing route meet the standard’s allowed processes, but not every commercial grade automatically qualifies. It fits Green Chemistry best when made through fermentation or enzymatic lipid processing with traceable renewable inputs and low-residue purification.
How does Ceramide 6-II work chemically?
The molecule is a sphingolipid with a long-chain base linked by an amide bond to a hydroxy fatty acid, which helps it pack into ordered lamellar layers with cholesterol and fatty acids. Typical use levels are often around 0.01% to 0.5%, and it is oil-dispersible rather than water-soluble, so it is commonly pre-dispersed into lipid phases, liposomes, or lamellar emulsifier systems.
Last updated 2026-05-13