Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde[5][6] ●
TL;DR. This ingredient is a synthetic fragrance material used to add a floral, clean scent profile to perfumes and scented personal care products.
What does Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde[5][6] do in a cosmetic formula?
This ingredient is a synthetic fragrance material used to add a floral, clean scent profile to perfumes and scented personal care products.
Is Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde[5][6] clean?
From a clean beauty perspective, it has major friction because it is a well-documented fragrance sensitizer and is prohibited in EU cosmetic products. It is also a common restricted-list flag for brands that screen fragrance allergens closely.
Is Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde[5][6] sustainable?
This material is synthetic and typically petrochemical-derived rather than sourced from renewable botanical feedstocks. Its sustainability profile is limited by low renewable-content alignment, fragrance-allergen concerns, and incomplete end-of-life advantages compared with readily biodegradable natural aroma materials.
Is Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde[5][6] COSMOS-approved?
It is not permitted under COSMOS-natural or COSMOS-organic standards as a synthetic fragrance molecule, and its EU cosmetic prohibition makes it incompatible with those frameworks. It has weak Green Chemistry alignment because it relies on synthetic aroma chemistry and carries a strong sensitization concern rather than a benign-use profile.
How does Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde[5][6] work chemically?
The molecule is an unsaturated alicyclic aldehyde with a hydroxylated side chain, a structure that can react with skin proteins directly or after oxidation, which is central to its sensitization profile. Historically it appeared at trace to low fragrance levels in finished products, often well below 0.1%, but regulators concluded that no broadly safe cosmetic exposure level could be established.
Last updated 2026-05-13