Methyl Diisopropyl Propionamide

TL;DR. It is a sensory cooling agent used to give skin, scalp, lip, or oral-care products a cool feel without relying on evaporation. It mainly modifies product perception rather than providing moisturization, cleansing, preservation, or UV protection.

What does Methyl Diisopropyl Propionamide do in a cosmetic formula?

It is a sensory cooling agent used to give skin, scalp, lip, or oral-care products a cool feel without relying on evaporation. It mainly modifies product perception rather than providing moisturization, cleansing, preservation, or UV protection.

Is Methyl Diisopropyl Propionamide clean?

From a clean-beauty perspective, this ingredient has friction because it is a fully synthetic sensory additive and can feel sharp or irritating at higher levels, especially around eyes, lips, or mucosa. It is not a major regulated allergen, but its value is mostly experiential, so stricter natural-leaning standards are less aligned with it.

Is Methyl Diisopropyl Propionamide sustainable?

This material is typically synthetically produced from petrochemical or mixed petrochemical feedstocks, rather than directly sourced from renewable plant or mineral inputs. Public biodegradability and aquatic-fate data are limited, which weakens its sustainability profile despite its low use level.

Is Methyl Diisopropyl Propionamide COSMOS-approved?

It is not permitted in COSMOS-organic or COSMOS-natural formulations because it falls outside the standard’s accepted natural, naturally derived, and specifically allowed synthetic categories. From a Green Chemistry view, its low-dose performance is efficient, but the synthetic feedstock route and limited biodegradation transparency are drawbacks.

How does Methyl Diisopropyl Propionamide work chemically?

The molecule is a small branched aliphatic amide that activates cold-sensing TRPM8 receptors, creating a cooling signal without menthol’s odor profile. Typical use is often in the low tenths of a percent, with careful dosing because sensory intensity rises quickly and it usually needs suitable solubilization in oil phases, surfactant systems, or flavor and fragrance blends.

Last updated 2026-05-13