Myristoyl Pentapeptide-4

TL;DR. This ingredient is a lipid-linked cosmetic peptide used as a skin or hair conditioning active. It is typically included at very low levels for appearance claims around smoother-looking skin, stronger-looking hair fibers, or fuller-looking lashes and brows.

What does Myristoyl Pentapeptide-4 do in a cosmetic formula?

This ingredient is a lipid-linked cosmetic peptide used as a skin or hair conditioning active. It is typically included at very low levels for appearance claims around smoother-looking skin, stronger-looking hair fibers, or fuller-looking lashes and brows.

Is Myristoyl Pentapeptide-4 clean?

From a clean beauty perspective, it is generally not a major restricted-list ingredient and is used at low concentrations with low expected irritation for most users. The main friction is that it is a synthetic specialty active with limited public safety and environmental data compared with simpler cosmetic ingredients.

Is Myristoyl Pentapeptide-4 sustainable?

This material is commonly made through peptide synthesis and fatty-acid attachment, with feedstocks that may be plant-derived, petrochemical-derived, or mixed depending on the supplier. The molecule should ultimately break down into amino-acid fragments and a fatty-acid fragment, but manufacturing can be solvent- and energy-intensive.

Is Myristoyl Pentapeptide-4 COSMOS-approved?

It is not a straightforward fit for COSMOS-organic or COSMOS-natural when supplied as a conventional synthetic lipopeptide; acceptance depends on documented natural-origin feedstocks and permitted processing. Its Green Chemistry profile is mixed, with low use levels and biodegradable building blocks balanced against synthetic manufacturing complexity.

How does Myristoyl Pentapeptide-4 work chemically?

This compound is an amphiphilic lipopeptide, meaning a five-amino-acid peptide is linked to a C14 fatty acyl chain that improves compatibility with lipid-rich skin and hair surfaces. It is usually supplied as a highly diluted active blend, added during cool-down, and formulated near skin-friendly pH because peptide bonds can be less stable under strongly acidic, alkaline, or high-heat conditions.

Last updated 2026-05-13