Oligopeptide-29

TL;DR. This ingredient is used mainly as a skin-conditioning signal ingredient in leave-on formulas, where it supports claims around smoother-looking, firmer-looking, or renewed-looking skin. It is typically present at low active levels rather than as a bulk moisturizer or structural base ingredient.

What does Oligopeptide-29 do in a cosmetic formula?

This ingredient is used mainly as a skin-conditioning signal ingredient in leave-on formulas, where it supports claims around smoother-looking, firmer-looking, or renewed-looking skin. It is typically present at low active levels rather than as a bulk moisturizer or structural base ingredient.

Is Oligopeptide-29 clean?

From a clean-beauty perspective, this ingredient is generally viewed as low-irritation and not a common allergen. The main caveat is that it is usually a lab-made, highly processed specialty ingredient, so it may not fit stricter natural-standard definitions.

Is Oligopeptide-29 sustainable?

This material is typically made through controlled synthesis rather than direct agricultural extraction. It is expected to break down into smaller amino-acid fragments over time, but its sustainability profile depends on manufacturing efficiency, solvents, and supplier practices.

Is Oligopeptide-29 COSMOS-approved?

This ingredient is not typically aligned with COSMOS-organic positioning because it is generally a synthetic specialty material, and COSMOS acceptance would depend on the exact manufacturing route and certifier review. From a Green Chemistry perspective, its low use level and degradable amino-acid structure are favorable, while synthesis complexity and processing inputs are the tradeoffs.

How does Oligopeptide-29 work chemically?

The molecule is a short, sequence-defined chain of amino acids, designed to interact with skin biology at very low concentrations in water-based or emulsion systems. It is usually formulated in the cool-down phase with attention to pH, microbial preservation, and protease exposure, since extreme pH, high heat, or enzyme activity can reduce integrity.

Last updated 2026-05-13