Pentasodium Tetracarboxymethyl Palmitoyl Dipeptide-12

TL;DR. This ingredient is a skin-conditioning peptide active used in facial serums and creams to support the appearance of firmness, elasticity, and fine lines. It is not a bulk solvent, emulsifier, surfactant, or preservative.

What does Pentasodium Tetracarboxymethyl Palmitoyl Dipeptide-12 do in a cosmetic formula?

This ingredient is a skin-conditioning peptide active used in facial serums and creams to support the appearance of firmness, elasticity, and fine lines. It is not a bulk solvent, emulsifier, surfactant, or preservative.

Is Pentasodium Tetracarboxymethyl Palmitoyl Dipeptide-12 clean?

It is not a common clean-standard restricted-list ingredient, and low-use peptide actives are generally judged more on substantiation, residual solvents, and carrier systems than on broad irritation concerns. Sensitive users can still react to the finished blend, especially if it includes penetration enhancers, fragrance, or assertive preservatives.

Is Pentasodium Tetracarboxymethyl Palmitoyl Dipeptide-12 sustainable?

This material is typically made through multi-step synthesis using amino-acid chemistry plus a C16 fatty-chain feedstock that may be palm-derived or petrochemical-derived, depending on the supplier. Public biodegradability and aquatic-fate data are limited, and the very low use level lowers formula load but does not make it a strong sustainability profile.

Is Pentasodium Tetracarboxymethyl Palmitoyl Dipeptide-12 COSMOS-approved?

It is generally not permitted in COSMOS-organic or COSMOS-natural products unless a supplier has specific documentation showing compliance under the standard. From a Green Chemistry view, the main friction points are multi-step synthesis, unclear renewable content, and limited biodegradation data, balanced by low use levels and water-compatible salt form.

How does Pentasodium Tetracarboxymethyl Palmitoyl Dipeptide-12 work chemically?

It is an amphiphilic it salt built from a short amino-acid chain, a C16 lipid tail, and multiple carboxymethyl groups, which gives it both skin affinity and water dispersibility. It is normally used at very low active levels in supplier blends, with formulation attention to mild acidic-to-neutral pH, electrolyte compatibility, preservation, and limited heat exposure during processing.

Last updated 2026-05-15