Red 22/Ci 45380

TL;DR. This ingredient is a synthetic colorant used to give cosmetics and personal-care products a pink to red hue, especially in lip, cheek, and makeup products. It has no skin-care activity and is used for visual shade control.

What does Red 22/Ci 45380 do in a cosmetic formula?

This ingredient is a synthetic colorant used to give cosmetics and personal-care products a pink to red hue, especially in lip, cheek, and makeup products. It has no skin-care activity and is used for visual shade control.

Is Red 22/Ci 45380 clean?

From a clean-beauty perspective, it has friction because many frameworks limit or exclude synthetic petroleum-derived colorants and coal-tar-derived dye categories due to sensitization and trace-impurity questions. In regulated cosmetics, it is allowed only within applicable color-additive specifications, including purity limits and permitted product categories.

Is Red 22/Ci 45380 sustainable?

This material is synthetically produced from petrochemical aromatic feedstocks and includes halogenated chemistry, so it does not have a strong renewable-sourcing profile. It is not a readily biodegradable botanical or mineral color source, and synthetic dyes can add aquatic color load if manufacturing wastewater is not tightly controlled.

Is Red 22/Ci 45380 COSMOS-approved?

It is not permitted in COSMOS-organic or COSMOS-natural products because the standard does not allow this type of synthetic organic colorant. Its Green Chemistry fit is weak, with nonrenewable feedstocks, multi-step synthesis, halogenation, and limited biodegradability.

How does Red 22/Ci 45380 work chemically?

The molecule is an anionic, brominated xanthene dye whose color comes from an extended conjugated ring system and salt-form ionization, giving strong visible absorption and often fluorescence. It is used at low colorant levels, typically well below 1% and often in the 0.001% to 0.1% range, with shade and solubility influenced by pH, counterions, and whether it is used as a soluble dye or as a permitted lake pigment.

Last updated 2026-05-13