Sh-polypeptide-47 ●
TL;DR. It is used mainly as a skin-conditioning bioactive, included at very low levels to support cosmetic claims around smoother, firmer, or more resilient-looking skin. It is not a structural emulsifier, solvent, or preservative.
What does Sh-polypeptide-47 do in a cosmetic formula?
It is used mainly as a skin-conditioning bioactive, included at very low levels to support cosmetic claims around smoother, firmer, or more resilient-looking skin. It is not a structural emulsifier, solvent, or preservative.
Is Sh-polypeptide-47 clean?
From a clean-beauty perspective, it is not a common fragrance allergen or major restricted-list material, but it carries biotech scrutiny because quality depends on purification, residual host-cell proteins, and endotoxin controls. Sensitivity is possible with any protein-based ingredient, especially on reactive skin.
Is Sh-polypeptide-47 sustainable?
This material is typically made by controlled fermentation rather than extraction from plants, minerals, or animals. Its low use level is a sustainability plus, and as a peptide it is expected to break down enzymatically, but genetically engineered microbial production creates natural-standard friction.
Is Sh-polypeptide-47 COSMOS-approved?
It is generally not aligned with COSMOS-organic or COSMOS-natural when produced through genetically modified microorganisms. It has some Green Chemistry positives, such as aqueous fermentation and very low dosing, but GMO-derived production and purification demands limit its fit.
How does Sh-polypeptide-47 work chemically?
The molecule is a single-chain polypeptide made from amino acids, so its performance depends on sequence integrity, folding, and protection from proteolysis or hydrolysis. It is usually supplied as a very dilute aqueous solution and used at ppm-range active levels, with formulation kept near skin-friendly pH and away from high heat.
Last updated 2026-08-18