Tetrapepide-21 ●
TL;DR. It functions as a skin-conditioning signal peptide, used at very low levels to support smoother-looking skin and collagen-related appearance claims rather than to preserve or cleanse a formula.
What does Tetrapepide-21 do in a cosmetic formula?
It functions as a skin-conditioning signal peptide, used at very low levels to support smoother-looking skin and collagen-related appearance claims rather than to preserve or cleanse a formula.
Is Tetrapepide-21 clean?
Clean-beauty friction is usually low: it is not a fragrance allergen, formaldehyde donor, ethoxylated surfactant, or high-sensitization preservative. Sensitivity is uncommon, though any peptide blend should be checked for its carrier solvent and preservative system.
Is Tetrapepide-21 sustainable?
This material is usually made by synthetic peptide chemistry rather than direct agricultural extraction. The finished molecule is expected to break down like other small peptides, but upstream manufacturing can carry a higher solvent and reagent footprint.
Is Tetrapepide-21 COSMOS-approved?
It is not automatically permitted under COSMOS-natural or COSMOS-organic standards; acceptance depends on whether the commercial grade meets the standard’s raw-material rules and documentation. It aligns partly with Green Chemistry through low use level and a biodegradable amino-acid structure, while conventional synthesis is less aligned because of protected amino acids, coupling reagents, and solvent use.
How does Tetrapepide-21 work chemically?
This ingredient is a short four-amino-acid signaling peptide, typically supplied as a dilute aqueous or humectant-based solution for leave-on skin care. Finished formulas often use supplier blends around 0.5 to 5%, delivering the neat molecule at much lower ppm levels, and formulators generally protect it from extreme pH, proteases, and prolonged high heat.
Last updated 2026-08-20