Acetyl Dipeptide-31 Amide

TL;DR. This ingredient functions as a skin-conditioning signaling peptide in leave-on products, mainly supporting claims around smoother-looking and firmer-feeling skin. It is not a preservative, surfactant, or emulsifier, so it is usually used as a low-level active within a serum, cream, or treatment formula.

What does Acetyl Dipeptide-31 Amide do in a cosmetic formula?

This ingredient functions as a skin-conditioning signaling peptide in leave-on products, mainly supporting claims around smoother-looking and firmer-feeling skin. It is not a preservative, surfactant, or emulsifier, so it is usually used as a low-level active within a serum, cream, or treatment formula.

Is Acetyl Dipeptide-31 Amide clean?

From a clean-beauty perspective, it is generally low-use and not a common restricted-list focus. The main caveats are its synthetic modification, supplier-dependent manufacturing residues, and the need for substantiated irritation and purity data.

Is Acetyl Dipeptide-31 Amide sustainable?

This material is typically made through peptide synthesis or biotechnology starting from amino-acid feedstocks, with very low finished-formula use levels. Its sustainability profile depends on solvent management, purification efficiency, and supplier biodegradability data, rather than bulk agricultural sourcing.

Is Acetyl Dipeptide-31 Amide COSMOS-approved?

It is not typically counted toward COSMOS-organic content, and COSMOS-natural alignment depends on whether the supplier can document approved feedstocks, allowed processing, and compliant residuals. Green Chemistry alignment is partial, because the molecule is small and used at low levels, but conventional peptide synthesis can involve coupling reagents and purification solvents.

How does Acetyl Dipeptide-31 Amide work chemically?

The molecule is a short modified peptide with terminal acetylation and amidation, changes that can improve stability and skin affinity compared with an unmodified sequence. In formulas it is usually added during cool-down to water-based serums or emulsions, with the delivered active often in the ppm range and with care around high heat or extreme pH.

Last updated 2026-05-13