Glycyrrhetinic Acid ●
TL;DR. This ingredient is a skin-conditioning and soothing active, mainly used to calm visible redness and support comfort in leave-on skin care. It can also be used in formulas aimed at oily or reactive-looking skin.
What does Glycyrrhetinic Acid do in a cosmetic formula?
This ingredient is a skin-conditioning and soothing active, mainly used to calm visible redness and support comfort in leave-on skin care. It can also be used in formulas aimed at oily or reactive-looking skin.
Is Glycyrrhetinic Acid clean?
It is generally clean-standard compatible, with low sensitization potential at normal cosmetic use levels and no common restricted-list friction. Quality control matters because purified plant-derived actives depend on solvent choice, residuals testing, and consistent assay levels.
Is Glycyrrhetinic Acid sustainable?
This material is plant-derived, usually isolated from a root crop, so its footprint depends on agricultural practices, extraction solvent recovery, and purification efficiency. It is expected to biodegrade more readily than persistent synthetic film-formers or silicones, but responsible sourcing is still relevant where wild harvesting is part of the supply chain.
Is Glycyrrhetinic Acid COSMOS-approved?
It can be used in COSMOS-natural formulations when made from natural feedstock through permitted extraction or hydrolysis routes, while COSMOS-organic alignment depends on certified-organic source material and compliant processing documentation. From a Green Chemistry view, it fits best when renewable feedstock, solvent recovery, and low-residue purification are documented.
How does Glycyrrhetinic Acid work chemically?
The molecule is a pentacyclic triterpenoid acid with a carboxylic acid group and very low water solubility, so formulators often pre-disperse it in glycols, alcohol, oils, or solubilizer systems. Typical leave-on use is often around 0.05% to 0.5%, with formulation attention to dispersion, pH compatibility, and protection from strong oxidizing conditions.
Last updated 2026-05-13